Citrus aurantium L, belonging to the family Rutaceae, is widely distributed in China. Zhishi, the Chinese traditional name for Citrus aurantium, has long been a folk medicine in traditional Chinese medicine (TCMto improve indigestion and help stimulate the Qi (energy force).
It also has been a folk remedy in Italy since the 16th century for fevers like malaria and as an antiseptic. Recent studies have confirmed that Zhishi, replacing Ma Huang, can be used for treatment of obesity without the negative cardiovascular side effect.Synepherine is the main active compound found in the fruit of Citrus aurantium, which is effective in providing the energy boost (caloric expenditure), aiding the expulsion of wind, warming the stomach, improving the appetite, and increasing metabolic rate. Citrus aurantium is theorized to stimulate fat metabolism without the negative cardiovascular side effects experienced by some people using Ma Huang. It is also a mild aromatic expectorant, a nervine and a laxation for constipatio
Plant original: Citrus aurantium L.
Specifications: 98.0% Synephrine by HPLC
Molecular Formula: C9H13NO2
Molecular Mass: 167.20
CAS No: 94-07-5
In application of traditional Chinese medical science, it is used to dispel bloating and a lump in the abdomen and phlegm, and to cureedema, constipation, gastroptosis, prolapse of uterus and rectocele.Antitumour,prevent osteoporosis, reduce cholesterin and protect heart.Nerve protection and prevent diseases of degeneration of nerve.Relieve menopausal symptoms of women, improve bone metabolism and protect cardiovascular system, etc.
Information about the safety and efficacy of synephrine used as a single drug may be deduced from the foregoing review of the literature in this Article. This information is, by and large, not contended. However, there exists considerable controversy about the safety and/or efficacy ofsynephrinecontaining preparations, which are often confused with synephrine alone, sometimes with synephrine, and much has been written about such preparations in the medical literature and on the Internet. Since this body of literature deals with mixtures containing synephrine as only one of several biologicallyactive components, even, in some cases, without explicit confirmation of the presence of synephrine, further discussion is outside the scope of this article.
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