1>Sources and Habitation
Indole-3-carbinol is produced by the breakdown of the glucosinolate glucobrassicin, which can be found at relatively high levels in cruciferous vegetables such as broccoli,cabbage, cauliflower, brussels sprouts, collard greens and kale. I3C is also available in a dietary supplement.
2>Descriptions and Specifications of Product
Plant original: Brassica oleracea L. var. botrytis L.
Specifications: 98.0% Indole-3-Carbinol Test by HPLC
Molecular Formula: C15H10O5
Molecular Mass: 270.24
CAS No: 520-36-5
1> Funcation and Application
Indole-3-carbinol is the subject of on going Biomedical research into its possible anticarcinogenic, antioxidant, and anti-atherogenic effects. Research on indole-3-carbinol has been conducted primarily using laboratory animals and cultured cells. Limited and inconclusive human studies have been reported.
A recent review of the biomedical research literature found that “evidence of an inverse association between cruciferous vegetable intake and breast or prostate cancer in humans is limited and inconsistent” and “larger randomized controlled trials are needed” to determine if supplemental indole-3-carbinol has health benefits.
2> Safety Concerns
There is evidence suggesting that indole-3-carbinol may have an effect on human papilloma virus infected cells in both pediatrics and adult patients.
3> Dosage Information
For treating abnormal cells on the surface of the cervix (cervical dysplasia): 200-400 mg per day has been used. However, 200 mg seems to be as effective as the higher dose.
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