Citrus aurantium L, belonging to the family Rutaceae, is widely distributed in China. Zhishi, the Chinese traditional name for Citrus aurantium, has long been a folk medicine in traditional Chinese medicine (TCM)to improve indigestion and help stimulate the Qi (energy force). It also has been a folk remedy in Italy since the 16th century for fevers like malaria and as an antiseptic. Recent studies have confirmed that Zhishi, replacing Ma Huang, can be used for treatment of obesity without the negative cardiovascular side effect
2>. Hesperidin can inhibit following enzymes: Phospholipase A2, lipoxygenase, HMG-CoA reductase and cyclo-oxygenase.
3>. Hesperidins improve the health of capillaries by reducing the capillary permeability.
4>.Hesperidin is used to reduce hay fever and other allergic conditions by inhibiting the release of histamine from mast cells. The possible anti-cancer activity of hesperidin could be explained by the inhibition of polyamine synthesis.
1>.Applied in food field, it is used as a flavor enhancer and sweetener in a wide variety of alcoholicbeverage, dessert foods and savory foods;
2>Applied in cosmetics, it can added into toothpaste and mouth wash ;
3>Applied in pharmaceutical field, it is mainly used to reducing the bitterness of in form.
Hesperidin is possibly safe for most people when used for less than three months. Side effects include stomach pain and upset, diarrhea, and headache.Do not use hesperidin if You are pregnant or breast-feeding.
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