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Genistein 2017-09-30T07:58:52+00:00

Project Description

Genistein

Name: Genistein

Specification: 98.0% Genistein Test by HPLC

Efficacy: Anti-estrogenic

CAS No: 446-72-0

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1> Sources and Habitation
Sophora japonica, Soybeans and soy foods are the major dietary sources of these substances. Nonfermented soy foods, such as tofu, contain higher levels of the genistein glycosides, while fermented soy foods, such as tempeh and miso, contain higher levels of the aglycone.
2> Descriptions and Specifications of Product
Plant original: Sophora japonica L.
Specifications: 98.0% Genistein Test by HPLC
Molecular Formula: C15H10O5
Molecular Mass: 270.24
CAS No: 446-72-0
1>Function and Application

Genistein is classified as a phytoestrogen which are plant-derived nonsteroidal  compounds  that possess  estrogen-like biological activity. Genistein has been found to have both weak estrogenic and weak anti-estrogenic effects.Genistein has weak estrogenic activity as measured in in vivo and in vitro assays. In vivo,its estrogenic activity is one-third that of glycitein and four times greater than that of daidzein.

Genistein has been found to have a number of antioxidant activities. It is a scavenger of reactive oxygen species and inhibits lipid peroxidation.It also inhibits superoxide anion generation by the enzyme xanthine oxidase. In addition, genistein, in animal experiments, has been found to increase the activities of the antioxidant enzymes superoxide dismutase, glutathione peroxidase, catalase and glutathione reductase.
2>Safety Concerns
Many of the often-cited genotoxic effects of genistein, including apoptosis, cell growth inhibition,  topoisomerase  inhibition and others become less obvious. Recent cellular, epigenetic and microarray studies are beginning to decipher genistein effects that occur at dietarily relevant low concentrations. In toxicology, the well accepted principle of “the dose defines the poison” applies to many toxicants and can be invoked, as herein, to distinguish genotoxic versus potentially beneficial in vitro effects of natural dietary products such as genistein.
3> Dosage Information
In consideration of levels of dietary genistein uptake and bioavailability we have defined in vitro concentrations of genistein >5 microM as non-physiological, and thus “high” doses.
The Information had not been evaluated by the Food and Drug Administration, only for reference
1> The safest natural ingredients and solutions provided as well.
2> Plant and select the most natural and nutritional raw materials.
3> 27 researching stuff and 4 manufacturing sites
4> GMP quality management system during the whole production process
5> Produce flexibly for bulk order or a small batch
6> Quickest response and fastest delivery
7> Our products sell to 96500 customers and over 120 countries
8> Professional service from SCIPHAR team’s enthusiasm and vigorous

Packaging and Shipping:

1>1KG/bag, 10KG/carton,25kg/drum

2>Shipping:

By Express:

Door to door;DHL/FEDEX/EMS;3-4DAYS; Suitable for under 50kg; high cost;easy to pick up the goods

By Air:

Airport to Airport;4-5 days;Suitable for more than 50kg;high cost;professional broker needed

By Sea:

Port to Port;15-30days; Suitable for more than 500kg;Low cost;professional broker needed

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