1>Sources and Habitation
20-Hydroxyecdysone (ecdysterone or 20E) is a naturally occurring ecdysteroid hormone which controls the ecdysis and metamorphosis of arthropods. It is one of the most common moulting hormones in insects, crabs, etc. It is also a phytoecdysteroid produced by various plants, including Cyanotis vaga, where its purpose is presumably to disrupt the development and reproduction of insect pests.
2>Descriptions and Specifications of Product
Plant original: Cyanotis arachnoidea CB Clarke
Specifications: 95.0% Ecdysterone Test by HPLC
Molecular Formula: C27H44O7
Molecular Mass: 480.63
CAS No: 5289-74-7
1> Funcation and application
Ecdysterone and other ecdysteroids are marketed as ingredients in nutritional supplements for various sports, particularly bodybuilding.A comprehensive study, designed to find any strength or athletic improvement from 20-hydroxyecdysone was published in 2006. The study looked for improvement in actual exercises performed and tested for improvements/increases in chemical indicators such as body composition and free/available testosterone. 20-Hydroxyecdysone and other ecdysteroids are used in biochemistry research as inducers in transgenic animals, whereby a new gene is introduced into an animal so that its expression is under the control of an introduced ecdysone receptor. Adding or removing ecdysteroids from the animal’s diet then gives a convenient way to turn the inserted gene on or off. At usual doses, 20-hydroxyecdysone appears to have little or no effect on animals that do not have extra genes inserted; it also has high bioavailability when taken orally, so it is useful for determining whether the transgene has been taken up effectively. For uses in gene therapy, it may be necessary to investigate more thoroughly the natural sources of ecdysteroids in humans.There is some in vitro evidence to show that 20-hydroxyecdysone has effects on some kinds of blood cells such as lymphocytes and neutrophils, and may act as an immunomodulator.
The great thing about Beta-Ecdysterone is that it helps maintain a positive nitrogen balance and increased protein synthesis without any negative side effects. This was the beginning of over 50 studies showing theremarkable effects of Beta-Ecdysterone on the body while simultaneously showing no side effects.
All the extensive research that shows Beta-Ecdysterone to be truly effective used dosages of at least 500mg per day and the best results were shown at even higher dosages of 2,000mg per day.
The Information had not been evaluated by the Food and Drug Administration, only for reference
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