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Apigenin 2017-09-30T07:30:50+00:00

Project Description

Apigenin

Name: Apigenin

Specification: 98.0% Apigenin Test by HPLC

Efficacy: Anti-inflammatory

CAS No: 520-36-5

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1>Sources and Habitation
Apigenin (4,5,7-trihydroxyflavone),  is a natural product belonging to the flavoneclass  that  is the aglycone  of  several naturally occurring glycosides.It is found in high amounts in several herbs including parsley, thyme, and peppermint.
It is is also found in a number of other herbs, including chamomile herb, Horsetail herb, lemon balm herb, perilla herb, vervain herb, and yarrow.
Red wine and tomato sauce contain this flavonoid.
2>Descriptions and Specifications of Product
Plant original: Apium graveolens var.dulce
Specifications: 98.0% Apigenin Test by HPLC
Molecular Formula: C15H10O5
Molecular Mass: 270.24
CAS No: 520-36-5
1>Function and Application

Apigenin is an antioxidant plant flavanoid which contains anti-inflammatory  and anticancer properties.  It may induce apoptosis and may inhibit proliferation of tumor cells by arresting the cell cycle at the G2/M phase.

Apigenin Is also known to be a MAP kinase inhibitor and a selective inhibitor of Protein Kinase 2 (CK2). Apigenin is capable of exerting diverse effects on a vast variety of molecular targets. Most effects appear to be mostly mediated through suppressing nitric oxide synthase-2 (NOS2), Hypoxia-inducible factor 1 α (HIF-1α), lipoxygenase, cyclooxygenase-2 (COX-2)  and  vascular  endothelial growth factor (VEGF) expression. Blocks proliferation of Wnt-1 transfected cells,  dephosphorylates β-catenin and lowers levels of β-catenin  and Dvi. Apigenin is  an inhibitor  of Casein Kinase, CYP19, CYP2C9, ERK and PKC.

2> Safety Concerns
Apigenin seems to be very safe chemical, without any dangerous side effects, flavonoid can interact with chemotherapy drugs.
It is, by itself, a potent chemotherapeutic agent.
3> Dosage Information
For general health and well-being, doses found in multiple servings of fruits and vegetables is adequate.For anxiolytic effects, doses in the range of 3-10 mg/kg  bodyweight  are effective without  sedation,  and higher doses induce sedation in addition to reductions in anxiety.
The Information had not been evaluated by the Food and Drug Administration, only for reference
1> The safest natural ingredients and solutions provided as well.
2> Plant and select the most natural and nutritional raw materials.
3> 27 researching stuff and 4 manufacturing sites
4> GMP quality management system during the whole production process
5> Produce flexibly for bulk order or a small batch
6> Quickest response and fastest delivery
7> Our products sell to 96500 customers and over 120 countries
8> Professional service from SCIPHAR team’s enthusiasm and vigorous

Packaging and Shipping:

1>1KG/bag, 10KG/carton,25kg/drum

2>Shipping:

By Express:

Door to door;DHL/FEDEX/EMS;3-4DAYS; Suitable for under 50kg; high cost;easy to pick up the goods

By Air:

Airport to Airport;4-5 days;Suitable for more than 50kg;high cost;professional broker needed

By Sea:

Port to Port;15-30days; Suitable for more than 500kg;Low cost;professional broker needed

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